![SOLVED: The following is an example of a "directed ortho metallation reaction": L.sec-BuLi MeI CH3 NEt3 NEt2 THF -78°C MgO MeO The following is an example of a C-H activation reaction: (Ph2PdCl2) ( SOLVED: The following is an example of a "directed ortho metallation reaction": L.sec-BuLi MeI CH3 NEt3 NEt2 THF -78°C MgO MeO The following is an example of a C-H activation reaction: (Ph2PdCl2) (](https://cdn.numerade.com/ask_images/a6274ed563a84d7590bca76f0dd96f4c.jpg)
SOLVED: The following is an example of a "directed ortho metallation reaction": L.sec-BuLi MeI CH3 NEt3 NEt2 THF -78°C MgO MeO The following is an example of a C-H activation reaction: (Ph2PdCl2) (
![Directed ortho metalation - cross coupling connections. Remote lateral metalation - cyclization of 2-imino-2′-methyl biaryls to 9-aminophenanthrenes. A synthesis of the alkaloid piperolactam C - ScienceDirect Directed ortho metalation - cross coupling connections. Remote lateral metalation - cyclization of 2-imino-2′-methyl biaryls to 9-aminophenanthrenes. A synthesis of the alkaloid piperolactam C - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0040403997106700-gr1.gif)
Directed ortho metalation - cross coupling connections. Remote lateral metalation - cyclization of 2-imino-2′-methyl biaryls to 9-aminophenanthrenes. A synthesis of the alkaloid piperolactam C - ScienceDirect
Directed ortho-metalation–nucleophilic acyl substitution strategies in deep eutectic solvents: the organolithium base dictates the chemoselectivity - Chemical Communications (RSC Publishing)
![A) GMP metalation reaction with [Ru(terpy)(bpy)Cl]PF 6 ([Ru]Cl, 1)and... | Download Scientific Diagram A) GMP metalation reaction with [Ru(terpy)(bpy)Cl]PF 6 ([Ru]Cl, 1)and... | Download Scientific Diagram](https://www.researchgate.net/publication/310765590/figure/fig5/AS:668880531902481@1536484954302/A-GMP-metalation-reaction-with-RuterpybpyClPF-6-RuCl-1and-formation-of-the.png)